Clindamycin + benzoyl peroxide

Generic name
Clindamycin + benzoyl peroxide
Brand name
ATC Code
D10AF51
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Clindamycin + benzoyl peroxide

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

Resorption: after conversion to benzoic acid, benzoyl peroxide is partially absorbed by intact skin. There is only minimal absorption of clindamycin through the skin. Metabolization: benzoyl peroxide is converted to benzoic acid (primarily in the dermis) and then hippuric acid. Elimination: with the urine as hippuric acid.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Acne vulgaris
  • Cutaneous
    • ≥ 12 years

      • Apply to the affected skin once daily in the evening.

      • Duration of treatment:

        Maximum 12 weeks

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

ANTI-ACNE PREPARATIONS FOR TOPICAL USE

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Retinoids for topical use in acne
D10AD03
D10AD53
D10AD01
Peroxides
D10AE01
Antiinfectives for treatment of acne
D10AF01
D10AF02
D10AF51
Other anti-acne preparations for topical use
D10AX03

Reference

  1. Stiefel Laboratories (Ireland) Ltd., SmPC Duac (RVG 31531) 06-02-2013, www.geneesmiddeleninformatiebank.nl

Changes

Therapeutic Drug Monitoring


Overdose