Tetracycline

Generic name
Tetracycline
Brand name
ATC Code
J01AA07
Compare …

Tetracycline

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information is present at this moment.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Bacterial infections
  • Oral
    • 8 years up to 18 years
      • 20 - 40 mg/kg/day in 4 doses. Max: 1.000 mg/day. Max single dose: 250 mg/dose.
      • Duration of treatment:

        Until at least 2 days after the symptoms disappear. For at least 10 days in streptococcal infections

Renal impaiment in children > 3 months

Adjustment in renal impairment as specified:

GFR 50-80 ml/min/1.73 m2
No adjustment required
GFR 30-50 ml/min/1.73 m2
No adjustment required
GFR 10-30 ml/min/1.73 m2
Do not administer
GFR < 10 ml/min/1.73 m2
Do not administer

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

(Irreversible) tooth discoloration in children, tooth development disorder.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications in children

Use in children < 8 years of age, due to risk of damage to growing bone and dental tissue and irreversible discoloration (yellow/gray/brown) of teeth

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Permanent discoloration of developing teeth: Hypoplasia of tooth enamel and permanent discoloration (yellow-gray-brown) of teeth have been reported with the use of tetracyclines during the second half of pregnancy or in children up to 8 years of age. This side effect is more common with long-term use of tetracyclines, but has also been reported after repeated short-term use.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

TETRACYCLINES

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Tetracyclines
J01AA02
J01AA08
J01AA12

Reference

  1. Pharmachemie BV, SmPC Tetracycline (RVG 50538) 17-12-2012, www.geneesmiddeleninformatiebank.nl

Changes

Therapeutic Drug Monitoring


Overdose