Deflazacort

Generic name
Deflazacort
Brand name
ATC Code
H02AB13

Deflazacort

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No pharmacokinetic data in children available (SmPC)

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Inflammatory diseases, endocrinologic diseases, neoplastic diseases
  • Oral
    • 6 years up to 18 years and ≥ 24 kg
      • (Deflazacort) 0.25 - 1.5 mg/kg/day in 1 dose. Max: 90 mg/day.
      • If sufficient response is achieved gradually reduce dosage to lowest possible maintenance dosage.

Duchenne muscular dystrofia (DMD)
  • Oral
    • 2 years up to 18 years
      • 0.9 mg/kg/day in 1 dose

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Growth retardation, cerebral pseudotumor, acute pancreatitis, posterior subcapsular cataract, idiopathic intracranial hypertension. [SmPC Calcort]

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Long-term use in children can cause  growth- and developmental delay.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Mineralocorticoids
H02AA02
Glucocorticoids
H02AB01
H02AB02
H02AB09
H02AB04
H02AB06
H02AB07
H02AB08
H02AB08

Reference

  1. Vital Pharma Nordic ApS, SmPC Deflazacort (RVG 124419) 19-01-2024, www.geneesmiddeleninformatiebank.nl

Changes

Therapeutic Drug Monitoring


Overdose