Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Magnesium chloride

Generic name
Magnesium chloride
Brand name
ATC Code
A12CC01

Pharmacokinetics in children

No information

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

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Available formulations

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Dosages

Hypomagnesaemia in convulsions
  • Intravenous
    • Term neonate
      • 10% magnesium chloride (0.5 mmol/ml): 0.08 mmol/kg/dose in 30 min.

      • Under ECG monitoring. Dose depending on the plasma concentration.

        No clinical studies have been carried out into the application of magnesium chloride in neonates with hypomagnesaemia and convulsions.
Maintenance requirement for magnesium in TPN
  • Intravenous
    • < 3 kg
      • 0.15 mmol/kg/day, continuous infusion.

      • Do not administer undiluted. Dose depending on the plasma concentration.
        Dosage corresponds to 0.3 ml/kg/day of 10% magnesium chloride (0.5 mmol/ml)

    • 3 up to 10 kg
      • 0.25 mmol/kg/day, continuous infusion.

      • Do not administer undiluted. Dose depending on the plasma concentration.
        Dosage corresponds to 0.5 ml/kg/day of 10% magnesium chloride (0.5 mmol/ml)

    • ≥ 10 kg
      • 0.12 mmol/kg/day, continuous infusion.

      • Do not administer undiluted. Dose depending on the plasma concentration.
        Dosage corresponds to 0.25 ml/kg/day of 10% magnesium chloride (0.5 mmol/ml)

         

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Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Watch out for arrhythmia and hypotension.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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Sodium
A12CA01
Zinc
A12CB01
Magnesium
A12CC05
A12CC04
A12CC03
A12CC02
Selenium
A12CE02
Other mineral products
A12CX
MAGNESIUM
A12CC05
A12CC04
A12CC03
A12CC02
OTHER MINERAL PRODUCTS
A12CX

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Reference

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007

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Changes

Changes