Pharmacokinetics in children
No information
dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
Available formulations
No information is present at this moment.
Dosages
| Aplastic anaemia and preparation for bone marrow transplant |
- Intravenous
-
1 month
up to
18 years
-
1 month
up to
18 years
|
| Rejection in kidney transplant |
|
|
Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Be aware of the possibility of anaphylactic responses and overfilling.
Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
IMMUNOSUPPRESSANTS
This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.
| Selective immunosuppressants |
|
|
|
L04AA24
|
|
|
|
L04AA32
|
|
|
|
L04AA13
|
|
|
|
L04AA02
|
|
|
|
L04AA06
|
|
|
|
L04AA31
|
|
|
|
L04AA44
|
| Other immunosuppressants |
|
|
|
L04AX01
|
|
|
|
L04AX03
|
| Tumor necrosis factor alpha (TNF-alpha) inhibitors |
|
|
|
L04AB04
|
|
|
|
L04AB01
|
|
|
|
L04AB06
|
|
|
|
L04AB02
|
| Interleukin inhibitors |
|
|
|
L04AC03
|
|
|
|
L04AC02
|
|
|
|
L04AC08
|
|
|
|
L04AC13
|
|
|
|
L04AC19
|
|
|
|
L04AC10
|
|
|
|
L04AC22
|
|
|
|
L04AC07
|
|
|
|
L04AC05
|
| Calcineurin inhibitors |
|
|
|
L04AD01
|
|
|
|
L04AD02
|
| Sphingosine-1-phosphate (S1P) receptor modulators |
|
|
|
L04AE01
|
| Janus-associated kinase (JAK) inhibitors |
|
|
|
L04AF02
|
|
|
|
L04AF02
|
|
|
|
L04AF08
|
|
|
|
L04AF01
|
| Monoclonal antibodies |
|
|
|
L04AG04
|
| Mammalian target of rapamycin (mTOR) kinase inhibitors |
|
|
|
L04AH02
|
|
|
|
L04AH01
|
| Complement inhibitors |
|
|
|
L04AJ01
|
|
|
|
L04AJ02
|
| Dihydroorotate dehydrogenase (DHODH) inhibitors |
|
|
|
L04AK02
|
Reference
-
Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
Therapeutic Drug Monitoring
Overdose