Flunarizine

Generic name
Flunarizine
Brand name
ATC Code
N07CA03

Flunarizine

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Migraine prophylaxis
  • Oral
    • 15 up to 40 kg
      • 5 mg/day in 1 dose
    • ≥ 40 kg
      • 5 - 10 mg/day in 1 dose

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

ANTIVERTIGO PREPARATIONS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Antivertigo preparations
N07CA52
N07CA02

References

  1. Boccia G, et al, Functional gastrointestinal disorders in migrainous children: efficacy of flunarizine, Cephalalgia, 2006, Oct;26(10), 1214-9
  2. Caers LI, et al, Flunarizine, a calcium-entry blocker, in childhood migraine, epilepsy, and alternating hemiplegia, Clin Neuropharmacol, 1987, Apr;10(2), 162-8
  3. Guidetti V, et al, Flunarizine and migraine in childhood. An evaluation of endocrine function, Cephalalgia, 1987, Dec;7(4), 263-6
  4. Holmes B, et al, Flunarizine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use, Drugs, 1984, Jan;27(1), 6-44
  5. Lastra Martinez L, et al, [Flunarizine and dihydroergotamine in the treatment of migraine in children], An Esp Pediatr., 1990, Mar;32(3), 213-8
  6. Pothmann R., [Prevention of migraine with flunarizine and acetylsalicylic acid. A double-blind study], Monatsschr Kinderheilkd., 1987, Sep;135(9), 646-9
  7. Sorge F, et al, Flunarizine in prophylaxis of childhood migraine. A double-blind, placebo-controlled, crossover study, Cephalalgia, 1988, Mar;8(1), 1-6
  8. Visudtibhan A, et al, Flunarizine for prophylactic treatment of childhood migraine, J Med Assoc Thai, 2004, Dec;87(12), 1466-70

Changes

Therapeutic Drug Monitoring


Overdose