Pharmacokinetics in children
No information
dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
Available formulations
No information is present at this moment.
Dosages
| Allergic conjunctivitis |
- Ocular
-
1 month
up to
18 years
-
1
drop(s)/dose
2-4x daily.
in both eyes.
|
Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
DECONGESTANTS AND ANTIALLERGICS
This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.
| Sympathomimetics used as decongestants |
|
|
|
S01GA01
|
| Other antiallergics |
|
|
|
S01GX07
|
|
|
|
S01GX01
|
|
|
|
S01GX06
|
|
|
|
S01GX08
|
|
|
|
S01GX09
|
References
-
Vermeulen J, et al, Comparison of the efficacy and tolerability of topical levocabastine and sodium cromoglycate in the treatment of seasonal allergic rhinoconjunctivitis in children, Pediatr Allergy Immunol, 1994, Nov;5(4), 209-13
-
Verin P, et al, Clinical evaluation of twice-daily emedastine 0.05% eye drops (Emadine eye drops) versus levocabastine 0.05% eye drops in patients with allergic conjunctivitis, Am J Ophthalmol, 2001, Jun;131(6), 691-8
-
Leonardi A, et al, Clinical and biological efficacy of preservative-free NAAGA eye-drops versus levocabastine eye-drops in vernal keratoconjunctivitis patients, Br J Ophthalmol., 2007, Dec;91(12), 1662-6
-
Whitcup SM, et al, Efficacy and tolerability of ophthalmic epinastine: a randomized, double-masked, parallel-group, active- and vehicle-controlled environmental trial in patients with seasonal allergic conjunctivitis., Clin Ther, 2004, Jan;26(1), 29-34
-
Bauer CP, et al, Efficacy and safety of intranasally applied dimetindene maleate solution. Multicenter study in children under 14 years suffering from seasonal allergic rhinitis, Arzneimittelforschung., 2001, 51(3), 232-7
-
Janssen-Cilag BV, SmPC Livocab (RVG 13968) 23-12-2014, www.geneesmiddeleninformatiebank.nl
Therapeutic Drug Monitoring
Overdose