Paraffin emulsion

Generic name
Paraffin emulsion
Brand name
ATC Code
A06AA01

Paraffin emulsion

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Therapy-resistant obstipation
  • Oral
    • 2 years up to 18 years
      • 1 - 2 ml/kg/day in 1 dose. Max: 90 ml/day.
      • Adjust depending on the effect.

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Inhalation, reflux or choking can cause lipoid pneumonia.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Watch out for inhalation by choking: lipoid pneumonitis. In prolonged use, check vitamins A, D and E (supplement if necessary) and check the blood clotting.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

DRUGS FOR CONSTIPATION

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Contact laxatives
A06AB02
A06AB08
A06AB06
A06AB06
A06AB58
Bulk-forming laxatives
A06AC01
Osmotically acting laxatives
A06AD12
A06AD11
A06AD65
A06AD65
A06AD15
A06AD65
Enemas
A06AG
A06AG10
A06AG10
A06AG04
A06AG11
A06AG01
Other drugs for constipation
A06AX01
A06AX02

References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. Kneepkens CMF, et al, Werkboek Kindergastro-enterologie, 2014, Derde druk
  3. Nederlandse Vereniging voor Kindergeneeskunde, Richtlijn Obstipatie bij kinderen 0-18 jaar, 2015

Changes

Therapeutic Drug Monitoring


Overdose