Hyaluronidase

Generic name
Hyaluronidase
Brand name
ATC Code
B06AA03
Compare …

Hyaluronidase

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Treatment extravasation injury
  • Infiltration
    • 1 month up to 18 years
      • 150 IU/dose, once only. inject into the extravasation area..

      • In vinca-alkaloids

    • Preterm and Term neonate
      • Solution 15 I.E./ml: 1 ml/dose divide over 5 injections around the extravasation site.

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

OVERIGE HEMATOLOGISCHE MIDDELEN

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Drugs used in hereditary angioedema
B06AC04
B06AC02
B06AC05

References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. Kamps WA et al, Werkboek ondersteundende behandeling kinderoncologie, VU Uitgeverij, 2005
  3. Gopalakrishnan PN, et al, Saline irrigation for the management of skin extravasation injury in neonates., Cochrane Database Syst Rev, 2017, 7(7), Cd008404
  4. Boyar V, et al., Point-of-Care Ultrasound Use in Neonatal Peripheral Intravenous Extravasation Injuries: A Case Series., J Wound Ostomy Continence Nurs, 2018, 45(6), 503-9
  5. Zenk KE, et al., Nafcillin extravasation injury. Use of hyaluronidase as an antidote., Am J Dis Child, 1981, 135(12), 1113-4

Changes

Therapeutic Drug Monitoring


Overdose