Levocabastine nasal spray

Generic name
Levocabastine nasal spray
Brand name
ATC Code
R01AC02

Levocabastine nasal spray

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

In children and adolescents aged between 6 and 17 years who received levocabastine nasal spray for four weeks (in varying doses up to a maximum of 0.2 mg four times a day), the plasma concentrations of levocabastine were either undetectable or ranged up to a maximum of 18.2 ng/ml. No comparison can be made with adults based on the little information that is available.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Allergic rhinitis
  • Nasal
    • 1 month up to 18 years
      • Per nostril: 2 puff(s)/dose 2-4x daily.

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Sympathomimetics, plain
R01AA08
R01AA05
R01AA09
R01AA07
Sympathomimetics, combinations excl. corticosteroids
R01AB01
Antiallergic agents, excl. corticosteroids
R01AC03
R01AC01
Corticosteroids
R01AD58
R01AD01
R01AD05
R01AD08
R01AD12
R01AD12
R01AD09
R01AD59
R01AD11
Other nasal preparations
R01AX10
OTHER NASAL PREPARATIONS
R01AX10

Reference

  1. Janssen-Cilag B.V., SmPC Livocab (RVG 13967) 11 sept 2013, www.cbg-meb.nl, Geraadpleegd 30 okt 2014

Changes

Therapeutic Drug Monitoring


Overdose