Simeticon

Generic name
Simeticon
Brand name
ATC Code
A03AX13
Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

Simeticon is not absorbed.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Flatulence, bloating
  • Oral
    • Term neonate
      • 27.7 mg/dose, as required, max. 4 x daily.

      • OPTIONAL (upon discretion of individual countries: add info on products/strenght of droplets)

        • 16 gtt Antiflat and Lefaxin-drops contain 41,2mg Simeticone.
        • 16gtt SAB-simplex contain 44,3mg Simeticone.
    • 1 month up to 6 years
      • 41.5 mg/dose, as required, max. 6 times daily.

      • OPTIONAL (upon discretion of individual countries: add info on products/strenght of droplets)

        • 16 gtt Antiflat and Lefaxin-drops contain 41,2mg Simeticone.
        • 16gtt SAB-simplex contain 44,3mg Simeticone.
    • 6 years up to 18 years
      • 55.4 - 83 mg/dose, as required 4-6 times daily.

      • OPTIONAL (upon discretion of individual countries: add info on products/strenght of droplets)

        • 16 gtt Antiflat and Lefaxin-drops contain 41,2mg Simeticone.
        • 16 gtt SAB-simplex contain 44,3mg Simeticone.

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Synthetic anticholinergics, esters with tertiary amino group
A03AA04
Synthetic anticholinergics, quaternary ammonium compounds
A03AB02
Other drugs for functional gastrointestinal disorders
A03AX15

Reference

  1. Gerot Lannach, SmPC Antiflat Tropfen (1-18340), 08/2016

Changes

Therapeutic Drug Monitoring


Overdose