Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Simeticon

Generic name
Simeticon
Brand name
ATC Code
A03AX13

Pharmacokinetics in children

Simeticon is not absorbed.

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Flatulence, bloating
  • Oral
    • Term neonate
      • 27.7 mg/dose, as required, max. 4 x daily.
      • OPTIONAL (upon discretion of individual countries: add info on products/strenght of droplets)

        • 16 gtt Antiflat and Lefaxin-drops contain 41,2mg Simeticone.
        • 16gtt SAB-simplex contain 44,3mg Simeticone.
    • 1 month up to 6 years
      • 41.5 mg/dose, as required, max. 6 times daily.
      • OPTIONAL (upon discretion of individual countries: add info on products/strenght of droplets)

        • 16 gtt Antiflat and Lefaxin-drops contain 41,2mg Simeticone.
        • 16gtt SAB-simplex contain 44,3mg Simeticone.
    • 6 years up to 18 years
      • 55.4 - 83 mg/dose, as required 4-6 times daily.
      • OPTIONAL (upon discretion of individual countries: add info on products/strenght of droplets)

        • 16 gtt Antiflat and Lefaxin-drops contain 41,2mg Simeticone.
        • 16 gtt SAB-simplex contain 44,3mg Simeticone.

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Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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Synthetic anticholinergics, esters with tertiary amino group
A03AA04
Synthetic anticholinergics, quaternary ammonium compounds
A03AB02
Other drugs for functional gastrointestinal disorders
A03AX15

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Reference

  1. Gerot Lannach, SmPC Antiflat Tropfen (1-18340), 08/2016

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Changes

Changes