Pharmacokinetics in children
No information
dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
Available formulations
No information is present at this moment.
Dosages
| Tapeworm (cattle, pigs, fish) |
- Oral
-
<
2 years
[1]
-
500
mg/dose,
once only.
- Directions for administration:
- The daily dose must be taken in one go after breakfast.
- The chewable tablets should be chewed into a fine paste and then swallowed with a small amount of water. The tablets can also be allowed to fall apart in water and then taken.
- For young children, the chewable tablets should be powdered finely before administration and given with a little water.
- It's recommended to drink sour fruit juices before the treatment with niclosamide to remove excess intestinal mucus. This way exposure of the tapeworm to the drug is enhanced.
- It's recommended to administer laxative treatment two hours after the last dose, especially in T. Solium infections, to prevent the development of cysticercosis
-
2 years
up to
6 years
[1]
-
1.000
mg/day,
once only.
- Directions for administration:
- The daily dose must be taken in one go after breakfast.
- The chewable tablets should be chewed into a fine paste and then swallowed with a small amount of water. The tablets can also be allowed to fall apart in water and then taken.
- For young children, the chewable tablets should be powdered finely before administration and given with a little water.
- It's recommended to drink sour fruit juices before the treatment with niclosamide to remove excess intestinal mucus. This way exposure of the tapeworm to the drug is enhanced.
- It's recommended to administer laxative treatment two hours after the last dose, especially in T. Solium infections, to prevent the development of cysticercosis
-
≥ 6 years
[1]
-
2.000
mg/dose,
once only.
- Directions for administration:
- The daily dose must be taken in one go after breakfast.
- The chewable tablets should be chewed into a fine paste and then swallowed with a small amount of water. The tablets can also be allowed to fall apart in water and then taken.
- For young children, the chewable tablets should be powdered finely before administration and given with a little water.
- It's recommended to drink sour fruit juices before the treatment with niclosamide to remove excess intestinal mucus. This way exposure of the tapeworm to the drug is enhanced.
- It's recommended to administer laxative treatment two hours after the last dose, especially in T. Solium infections, to prevent the development of cysticercosis
|
| Dwarf tapeworm |
- Oral
-
<
2 years
[1]
- Initial dose:
500
mg/dose,
once only on Day 1.
- Maintenance dose:
250
mg/day
in 1
dose Days 2 to 7.
- Directions for administration:
- The daily dose must be taken in one go after breakfast.
- The chewable tablets should be chewed into a fine paste and then swallowed with a small amount of water. The tablets can also be allowed to fall apart in water and then taken.
- For young children, the chewable tablets should be powdered finely before administration and given with a little water.
-
2 years
up to
6 years
[1]
- Initial dose:
1.000
mg/dose,
once only on Day 1.
- Maintenance dose:
500
mg/day
in 1
dose Days 2 to 7.
- Directions for administration:
- The daily dose must be taken in one go after breakfast.
- The chewable tablets should be chewed into a fine paste and then swallowed with a small amount of water. The tablets can also be allowed to fall apart in water and then taken.
- For young children, the chewable tablets should be powdered finely before administration and given with a little water.
-
≥ 6 years
[1]
- Initial dose:
2.000
mg/dose,
once only on Day 1.
- Maintenance dose:
1.000
mg/day
in 1
dose Days 2 to 7.
- Directions for administration:
- The daily dose must be taken in one go after breakfast.
- The chewable tablets should be chewed into a fine paste and then swallowed with a small amount of water. The tablets can also be allowed to fall apart in water and then taken.
- For young children, the chewable tablets should be powdered finely before administration and given with a little water.
|
Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
ANTICESTODALS
This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.
Reference
-
Bayer BV, SmPC Yomesan (RVG 00886) 09-10-2011, www.geneesmiddeleninformatiebank.nl
Therapeutic Drug Monitoring
Overdose
