Cyclizine

Generic name
Cyclizine
Brand name
ATC Code
R06AE03
Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information available about the pharmacokinetic parameters in children.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Nausea and vomiting, travel sickness
  • Oral
    • 6 years up to 12 years
      [1] [2]
      • 25 mg/dose, as required, max. 3x daily.

      • For travel sickness, take a tablet 1-2 hours before departure.

    • ≥ 12 years
      [1] [2]
      • 50 mg/dose, as required, max. 3x daily.

      • For travel sickness, take a tablet 1-2 hours before departure.

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Do not give to children aged under 1 year because the sedative effect could cause periods of respiratory arrest during sleep.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

ANTIHISTAMINES FOR SYSTEMIC USE

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Piperazine derivatives
R06AE07
Other antihistamines for systemic use
R06AX26
R06AX13

References

  1. Centrafarm BV, SmPC Cyclizine (RVG 52988) 21-05-2014, www.cbg-meb.nl
  2. KNMP, Zelfzorgstandaard Reisziekte, 2014

Changes

Therapeutic Drug Monitoring


Overdose