Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Cyclizine

Generic name
Cyclizine
Brand name
ATC Code
R06AE03

Pharmacokinetics in children

No information available about the pharmacokinetic parameters in children.

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Nausea and vomiting, travel sickness
  • Oral
    • 6 years up to 12 years
      [1] [2]
      • 25 mg/dose, as required, max. 3x daily.
      • For travel sickness, take a tablet 1-2 hours before departure.

    • ≥ 12 years
      [1] [2]
      • 50 mg/dose, as required, max. 3x daily.
      • For travel sickness, take a tablet 1-2 hours before departure.

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Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Do not give to children aged under 1 year because the sedative effect could cause periods of respiratory arrest during sleep.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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Piperazine derivatives
R06AE07
Other antihistamines for systemic use
R06AX26
R06AX13

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References

  1. Centrafarm BV, SmPC Cyclizine (RVG 52988) 21-05-2014, www.cbg-meb.nl
  2. KNMP, Zelfzorgstandaard Reisziekte, 2014

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Changes

Changes