Quinine

Generic name
Quinine
Brand name
ATC Code
P01BC01
Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information is present at this moment.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Treatment of uncomplicated malaria
  • Oral
    • < 8 years
      [1] [2]
      • 30 mg/kg/day in 3 doses. Max: 1.800 mg/day.
      • Duration of treatment:

        The length of treatment is up to 7 days after the patient no longer has a fever.

      • Directions for administration:

        The tablets should be taken after a meal.

      • Always in combination with clindamycin

    • ≥ 8 years
      [1] [2]
      • 30 mg/kg/day in 3 doses. Max: 1.800 mg/day.
      • Duration of treatment:

        The length of treatment is up to 7 days after the patient no longer has a fever.

      • Directions for administration:

        The tablets should be taken after a meal.

      • Always in combination with doxycycline

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

ANTIMALARIALS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Aminoquinolines
P01BA01
P01BA02
Biguanides
P01BB01
Methanolquinolines
P01BC02
Diaminopyrimidines
P01BD01
Artemisinin and derivatives, plain
P01BE03
Artemisinin and derivatives, combinations
P01BF01

References

  1. ARTECEF B.V., SPC A-QS 200 (RVG 52455) 2 maart 2012, www.cbg-meb.nl, Geraadpleegd 23 juli 2014
  2. LCR, Malariaprofylaxe bulletin 2013

Changes

Therapeutic Drug Monitoring


Overdose