Potassium chloride

Generic name
Potassium chloride
Brand name
ATC Code
A12BA01
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Potassium chloride

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Hypokalaemia
  • Oral
    • 1 month up to 18 years

      • Dose depending on the plasma potassium concentration.

  • Intravenous
    • 1 month up to 18 years
      [2]

      • Dose depending on the plasma potassium concentration, maximum of 2-3 mmol/kg/day

        Do not give undiluted as a bolus. Be aware of the potential for arrhythmia when infused too fast: the maximum concentration for a peripheral line: 0.08 mmol/ml, i.e. add a maximum of 40 mmol to 500 ml.
Maintenance requirement for potassium in TPN
  • Intravenous
    • < 3 kg
      [1]
      • 1 - 2 mmol/kg/day, continuous infusion.

      • = 1-2 ml/kg/day at a concentration of 7.5% (potassium concentration of 1 mmol/ml). Dose depending on the plasma concentration

    • ≥ 3 kg
      [1]
      • 1 - 3 mmol/kg/day, continuous infusion.

      • = 1-3 ml/kg/day at a concentration of 7.5% (potassium concentration of 1 mmol/ml). Dose depending on plasma concentration.

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Hyperkalaemia, gastrointestinal disorders (OR), intestinal ulcers (OR)

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Intravenous: Do not administer undiluted as a bolus. Be aware of the potential for arrhythmia when infused too fast: the maximum concentration for a peripheral line: 0.08 mmol/ml, i.e. add a maximum of 40 mmol to 500 ml.
Watch out for renal insufficiency and potassium sparing diuretics.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

POTASSIUM

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. Centrafarm Services BV, SPC Kaliumchloride (RVG 55104) 04-04-2018, www.cbg-meb.nl

Changes

Therapeutic Drug Monitoring


Overdose