Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Potassium chloride

Generic name
Potassium chloride
Brand name
ATC Code
A12BA01

Pharmacokinetics in children

No information

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Hypokalaemia
  • Oral
    • 1 month up to 18 years

      • Dose depending on the plasma potassium concentration.

  • Intravenous
    • 1 month up to 18 years
      [2]

      • Dose depending on the plasma potassium concentration, maximum of 2-3 mmol/kg/day

        Do not give undiluted as a bolus. Be aware of the potential for arrhythmia when infused too fast: the maximum concentration for a peripheral line: 0.08 mmol/ml, i.e. add a maximum of 40 mmol to 500 ml.
Maintenance requirement for potassium in TPN
  • Intravenous
    • < 3 kg
      [1]
      • 1 - 2 mmol/kg/day, continuous infusion.

      • = 1-2 ml/kg/day at a concentration of 7.5% (potassium concentration of 1 mmol/ml). Dose depending on the plasma concentration

    • ≥ 3 kg
      [1]
      • 1 - 3 mmol/kg/day, continuous infusion.

      • = 1-3 ml/kg/day at a concentration of 7.5% (potassium concentration of 1 mmol/ml). Dose depending on plasma concentration.

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Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Hyperkalaemia, gastrointestinal disorders (OR), intestinal ulcers (OR)

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Intravenous: Do not administer undiluted as a bolus. Be aware of the potential for arrhythmia when infused too fast: the maximum concentration for a peripheral line: 0.08 mmol/ml, i.e. add a maximum of 40 mmol to 500 ml.
Watch out for renal insufficiency and potassium sparing diuretics.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. Centrafarm Services BV, SPC Kaliumchloride (RVG 55104) 04-04-2018, www.cbg-meb.nl

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Changes

Changes