Charcoal, activated

Generic name
Charcoal, activated
Brand name
ATC Code
A07BA01
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Charcoal, activated

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

Is not absorbed.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

General Dose Info

  • The adsorption capacity of the pharmaceutical formulations varies; a suspension is more effective than tablets or capsules. In cases of intoxication, the suspension should therefore be used and not the tablets or capsules.

  • Combination with laxative:

    • When activated charcoal is administered once, laxative is indicated only when ingesting toxins that reduce intestinal peristalsis.

    • When activated charcoal is administered repeatedly, laxative is indicated on the basis of stool pattern.

    • Sodium sulfate as laxative: 0.5 g/kg/dose PO (max 30 g), repeat as necessary
      Caution: use of laxatives may induce electrolyte disturbances
      Source: NVIC

Dosages

Adsorbent for intoxications
  • Oral
    • 1 month up to 12 years
      [1] [2]
      • 1 g/kg/dose Repeat if needed.
    • 12 years up to 18 years
      [1] [2]
      • 50 - 100 g/dose, once only. Subsequent doses of 20 g/dose every 4-6 hours may be needed in severe intoxications.

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

The following substances do not bind to charcoal: acids, bases, alcohols, iron, lithium and cyanide.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

INTESTINAL ADSORBENTS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

References

  1. Norit NV, SmPC Norit (RVG 16135) 17-07-2023, www.geneesmiddeleninformatiebank.nl
  2. Nationaal Vergiftigingen Informatie Centrum , Handleiding geactiveerde kool toedienen, https://www.vergiftigingen.info/f?p=300:THERAPIE:7308656415462:::RP,1320:P1320_THERAP_NO:T23-&cs=3L23Iq7M15FeHAyMihFADR7xwP4Bek9QRnk0uddGvgt_ddNpqw5nxScvth3egfICD1IZREyu3l188SS9u7apT7Q, Geraadpleegd 08-10-2024

Changes

Therapeutic Drug Monitoring


Overdose