- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
The clearance of ipilimumab increases with increased bodyweight. The average clearance in children aged 12-18 years is 8.72 ml/hour
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Melanoma |
|---|
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Research data: in children (≥ 12 yrs, monotherapy), only start therapy after very careful consideration because of the very small amount of safety data and lack of data on long-term treatment.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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Reference
- Bristol-Meyers Squibb Pharma EEIG, SmPC Yervoy (EU1/11/698/001-002) 30-07-2018, www. geneesmiddeleninformatiebank.nl
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Changes
Changes
