- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
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Available formulations
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Dosages
| Hypotension (incl. orthostatic) |
|---|
|
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Renal impaiment in children > 3 months
Adjustment in renal impairment as specified:
GFR 50-80 ml/min/1.73 m2
Adjustment is not requiredGFR 30-50 ml/min/1.73 m2
Adjustment is not requiredGFR 10-30 ml/min/1.73 m2
Adjustment is not requiredGFR < 10 ml/min/1.73 m2
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Adrenergic and dopaminergic agents | ||
|---|---|---|
| C01CA24 | ||
| C01CA07 | ||
| C01CA04 | ||
| C01CA26 | ||
| C01CA02 | ||
| C01CA24 | ||
| C01CA03 | ||
| C01CA06 | ||
| Phosphodiesterase inhibitors | ||
|---|---|---|
| C01CE02 | ||
| Other cardiac stimulants | ||
|---|---|---|
| C01CX08 | ||
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References
- Chen L et al, Midodrine hydrochloride is effective in the treatment of children with postural orthostatic tachycardia syndrome, Circ J, 2011, 75(4), 927-931
- Qingyou Z, et al, The efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope, J Pediatr, 2006, 149(6), 777-780
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Changes
Changes
