- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information is present at this moment.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
On-label
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Available formulations
Per ml oordr.: Polymyxine-B-sulfaat 10000 IE Neomycinesulfaat 10 mg Fludrocortisonacetaat 1 mg Lidocaïnehydrochloride (als 1-water) 40 mg
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Dosages
| External ear inflammation, secondary infection with microorganisms that are susceptible to neomycin and/or polymyxin B-sulphate |
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Adult Side Effects
Irritatie en branderig gevoel. Algemene bijwerkingen kunnen na langdurig gebruik van corticosteroïden optreden. Overgevoeligheidsverschijnselen. Sensibilisatie door neomycine treedt frequent. Langdurig gebruik van corticosteroïden in het oor kan leiden tot atrofie en perforatie van het trommelvlies.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications in adults
Aandoeningen, primair veroorzaakt door een bacterie, virus, schimmel, gist of parasiet. Ulcereuze aandoeningen, wonden. Geperforeerd trommelvlies. Overgevoeligheid voor corticosteroïden of aminoglycosiden.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Corticosteroids and antiinfectives in combination | ||
|---|---|---|
| S02CA03 | ||
| S02CA03 | ||
| S02CA06 | ||
| S02CA07 | ||
| S02CA03 | ||
| S02CA03 | ||
| S02CA04 | ||
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Reference
- Zambon Nederland B.V., SmPC Panotile (RVG 06585) 09-02-2015, www.geneesmiddeleninformatiebank.nl
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Changes
Changes
