- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No data known on use in children.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Acute pain |
|---|
|
| Palliative care |
|---|
|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Intranasale toepassing leidt snel tot afhankelijkheid. Let op bij langdurig gebruik.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Natural opium alkaloids | ||
|---|---|---|
| N02AA03 | ||
| N02AA01 | ||
| N02AA05 | ||
| N02AA59 | ||
| Phenylpiperidine derivatives | ||
|---|---|---|
| N02AB03 | ||
| N02AB02 | ||
| Diphenylpropylamine derivatives | ||
|---|---|---|
| N02AC06 | ||
| N02AC03 | ||
| Oripavine derivatives | ||
|---|---|---|
| N02AE01 | ||
| Morphinan derivatives | ||
|---|---|---|
| N02AF02 | ||
| Other opioids | ||
|---|---|---|
| N02AX06 | ||
| N02AX01 | ||
| N02AX02 | ||
| Opioids in combination with non-opioid analgesics | ||
|---|---|---|
| N02AJ13 | ||
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References
- Hansen MS et al., Limited evidence for intranasal fentanyl in the emergency department and the prehospital setting--a systematic review, Dan Med J, 2013, Jan;60(1), A4563
- Harlos MS et al, Intranasal fentanyl in the palliative care of newborns and infants, J Pain Symptom Manage, 2013, Aug;46(2), 265-74
- Herd D et al., Intranasal fentanyl paediatric clinical practice guidelines, Emerg Med Australas, 2009, Aug;21(4), 335
- Mudd S et al, Intranasal fentanyl for pain management in children: a systematic review of the literature., J Pediatr Health Care, 2011, Sep-Oct;25(5), 316-22
- Pieper L et al., Intranasal fentanyl for respiratory distress in children and adolescents with life-limiting conditions, BMC Palliat Care, 2018, Sep 10;17(1), 106
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Changes
Changes
