Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Flurbiprofen

Generic name
Flurbiprofen
Brand name
ATC Code
R02AX01

Pharmacokinetics in children

No information available about the pharmacokinetic parameters in children.

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Sore throat
  • Oromucosal
    • ≥ 13 years
      • 8.75 mg/dose, as required, max. 5x daily.
      • Duration of treatment:

        Maximum 3 days

      • Directions for administration:

        Move the lozenge around in the mouth while sucking on it in order to avoid localized irritation.

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Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

In exceptional cases, varicella can lead to serious infectious complications of the skin and soft tissues. To date, it cannot be ruled out that NSAIDs contribute to the worsening of these infections. It is therefore recommended not to use flurbiprofen in cases of varicella Prescrire Internat. 2010)

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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References

  1. Reckitt Benckiser Healthcare BV, SmPC Strepfen suikervrij (RVG 109114) 24-06-2015, www.cbg-meb.nl
  2. KNMP, Zelfzorgstandaard Verkoudheid, griep en hoest, 2014
  3. <No author listed>, Varicella, herpes zoster and nonsteroidal anti-inflammatory drugs: serious cutaneous complications., Prescrire Internat, 2010, 19, 72-73

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Changes

Changes