Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Potassium citrate

Generic name
Potassium citrate
Brand name
ATC Code
A12BA02

Pharmacokinetics in children

Citrate is metabolized to the hydrogen carbonate. It is primarily excreted in the urine, with less than 5% in unchanged form.

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

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Available formulations

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General Dose Info

108 mg potassiumcitrate equals 0,33 mmol potassiumcitrate


Dosages

Kidney and bladder stones
  • Oral
    • 8 months up to 18 years
      • Potassium citrate: 108 - 216 mg/kg/day in 3 - 4 doses. Max: 8.6 g/day.
    • 8 months up to 18 years
      [1] [2] [3]
      • Potassium citrate: 108 - 216 mg/kg/day in 3 - 4 doses. Max: 8.6 g/day.

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Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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References

  1. Habbig S et al, Nephrocalcinosis and urolithiasis in children, Kidney Int, 2011, Dec;80(12):, 1278-91
  2. Karsli O et al, Metabolic risk factors and the effect of metaphylaxis in pediatric stone disease with hypocitraturia, Urolithiasis, 2013, Feb;41(1), 9-13
  3. Tekin A et al, Oral potassium citrate treatment for idiopathic hypocitruria in children with calcium urolithiasis, J Urol, 2002, Dec;168(6), 2572-4

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Changes

Changes