Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Antirhesus (D) immunoglobulin

Generic name
Antirhesus (D) immunoglobulin
Brand name
ATC Code
J06BB01

Pharmacokinetics in children

No specific data available about the pharmacokinetics in children.

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Incompatible transfusion of red blood cells
  • Intramuscular
    • 0 years up to 18 years
      • RhoPhylac, Rhesonativ: 50 IU per ml of transfused blood or 100 IU per ml of transfused erythrocytes
        RheDQuin: 100 IU per ml of transfused erythrocytes

      • After consultation with a transfusion specialist.
        If a large volume is required (> 2 ml for children or > 5 ml for adults) and intramuscular administration is chosen, it is recommended that this should be given in subdivided doses at multiple injection sites.

  • Intravenous
    • 0 years up to 18 years
      • RhoPhylac: 50 IU per ml of transfused blood or 100 IU per ml of transfused erythrocytes

      • After consultation with a transfusion specialist

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Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

In the event of a large volume needing to be administered (> 2 ml for children or > 5 ml for
adults), it is recommended that this should be given as two injections at different
sites.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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References

  1. Sanquin, SmPC RheDQuin (RVG 16928) 23-04-2010, www.cbg-meb.nl, Geraadpleegd 14-04-2014
  2. CSL Behring GmbH, SmPC Rhophylac (RVG 27449) 11-11-2013, www.cbg-meb.nl, Geraadpleegd 14-04-2014
  3. EuroCept bv, SmPC Rhesonativ (RVG 33233) 28 mrt 2014, www.cbg-meb.nl

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Changes

Changes