Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Fenoterol + ipratropium bromide

Generic name
Fenoterol + ipratropium bromide
Brand name
ATC Code
R03AL01

Pharmacokinetics in children

No information.

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

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Available formulations

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Dosages

Acute asthma attack
  • Inhalation
    • 1 month up to 18 years
      [1]
      • 2 puff(s)/dose, as required repeat after 5 minutes. Per puff: 50 micrograms fenoterol + 20 micrograms ipratropium.

      • Further inhalations may be needed.

    • Inhalation solution
      • < 6 years
        • Solution: 0,25 mg/ml ipratropiumbromide and 0,5 mg/ml fenoterolhydrobromide: 10 drop(s)/dose, once only.
      • 6 years up to 12 years
        • Solution: 0,25 mg/ml ipratropiumbromide and 0,5 mg/ml fenoterolhydrobromide: 10 - 40 drop(s)/dose, once only.
      • ≥ 12 years
        • Solution 0,25 mg/ml ipratropiumbromide and 0,5 mg/ml fenoterolhydrobromide: 20 - 50 drop(s)/dose, once only. Max: 80 drop(s)/dose.
Maintenance treatment for asthma
  • Inhalation
    • 1 month up to 18 years
      [1]
      • 1 - 2 puff(s)/dose, as required. Max: 8 puff(s)/day. Per puff: 50 micrograms fenoterol + 20 micrograms ipratropium.

      • FORMULATIONS
        0-12 months dosing aerosol + AeroChamber with a baby mask.
        1-4 yrs: dosing aerosol + AeroChamber with a child mask.
        > 4 yrs: dosing aerosol + AeroChamber with a mouthpiece.

    • Aerosol
      • 6 years up to 18 years
        • 1 - 2 puff(s)/dose, as required. Max: 8 puff(s)/day. Per puff: 50 micrograms fenoterol + 20 micrograms ipratropium.

        • FORMULATIONS
          0-12 months dosing aerosol + AeroChamber with a baby mask.
          1-4 yrs: dosing aerosol + AeroChamber with a child mask.
          > 4 yrs: dosing aerosol + AeroChamber with a mouthpiece.

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Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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Alpha- and beta-adrenoreceptor agonists
R03AA01
Selective beta-2-adrenoreceptor agonists
R03AC13
R03AC02
R03AC12
R03AC03
Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
R03AK08
R03AK11
R03AK10
R03AK07
R03AK06
Adrenergics in combination with anticholinergics incl. triple combinations with corticosteroids
R03AL02

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References

  1. Boehringen Ingelheim BV, SPC Berodual aerosol (RVG 14123), www.cbg-meb.nl, Geraadpleegd 8 juni 2012, http://db.cbg-meb.nl/IB-teksten/h14123.pdf
  2. Boehringer Ingelheim RCV GmbH & Co KG, SmPC Berodualin- Inhalation solution ( Z.Nr.: 17452), 09/2020

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Changes

Changes