- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
The general trend shows that plasma exposure to the free acid of travoprost after local administration of travoprost is extremely low in all age groups that were evaluated.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Glaucoma |
|---|
|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
Ocular hyperaemia, eyelash growth, eyelid erythema, keratitis, increased tear production and photophobia
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Parasympathomimetics | ||
|---|---|---|
| S01EB01 | ||
| Carbonic anhydrase inhibitors | ||
|---|---|---|
| S01EC01 | ||
| S01EC03 | ||
| Beta blocking agents | ||
|---|---|---|
| S01ED01 | ||
| Prostaglandin analogues | ||
|---|---|---|
| S01EE03 | ||
| S01EE01 | ||
| Other antiglaucoma preparations | ||
|---|---|---|
| S01EX | ||
| OTHER ANTIGLAUCOMA PREPARATIONS | ||
|---|---|---|
| S01EX | ||
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References
- SPC Travatan (Alcon Laboratories) 27/11/2006, EU/1/01/199/001-002 (02-03-2015)
- Yanovitch TL, et al, Travoprost in children: adverse effects and intraocular pressure response, J AAPOS, 2009, Feb;13(1), 91-3
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Changes
Changes
