- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Available formulations
No information is present at this moment.
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Dosages
| Vitamin A deficiency |
|---|
|
| Maintenance requirement |
|---|
|
| Supplementation in cystic fibrosis |
|---|
|
| Measles, xerophthalmia, reduction of mortality and morbidity |
|---|
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
Symptoms of acute intoxication have been observed in infants and young children after 75,000 IU: increased intracranial pressure, vomiting, hallucinations and dizziness.
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
In cystic fibrosis and bile duct atresia, measure the plasma concentration once every 6 months. In cystic fibrosis, in liver disease also measure serum 'retinol binding protein' and retinol esters annually in children [Maqbool].
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
| Vitamin D and analogues | ||
|---|---|---|
| A11CC05 | ||
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
References
- Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
- Kneepkens CMF et al, Werkboek Kindergastro-Enterologie, VU Uitgeverij, 2002, 2e druk
- Imdad A, et al, Vitamin A supplementation for preventing morbidity and mortality in children from 6 months to 5 years of age, Cochrane Database Syst Rev, 2010, (12):, CD008524
- Benn CS, et al, Randomised study of effect of different doses of vitamin A on childhood morbidity and mortality, BMJ, 2005, Dec 17;331(7530):, 1428-32
- Ross DA. , Recommendations for vitamin A supplementation. , J Nutr. , 2002, Sep;132(9 Suppl), 2902S-6S
- Sathe MN, et al, Update in pediatrics: focus on fat-soluble vitamins. , Nutr Clin Pract. , 2010, Aug;25(4), 340-6
- Maqbool A, et al, Update on fat-soluble vitamins in cystic fibrosis. , Curr Opin Pulm Med., 2008, Nov;14(6), 574-81
- Aristo Pharma GmbH, SmPC Vitadral® Tropfen (3000071.00.00), 05/2016
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Changes
Changes
