Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Selenium

Generic name
Selenium
Brand name
ATC Code
A12CE02

Pharmacokinetics in children

The absorption is approximately 45-95%

A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.

Available formulations

No information is present at this moment.

A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.

Dosages

Selenium deficiency
  • Oral
    • 1 month up to 1 year
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose
    • 1 year up to 4 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 60 microg./day.
    • 4 years up to 7 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 90 microg./day.
    • 7 years up to 11 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 130 microg./day.
    • 11 years up to 15 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 200 microg./day.
    • 15 years up to 18 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 250 microg./day.
Maintenance requirement for selenium in TPN
  • Intravenous
    • 1 month up to 18 years
      • 1 - 2 microg./kg/day, continuous infusion. Max: 30 microg./day.

A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.

References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. Biosyn Arzneimittel GmbH, SmPC Selenase (RVG 22907) 17-12-2014, www.geneesmiddeleninformatiebank.nl

A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.

Changes

Changes