- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No studies have been carried out into the pharmacokinetic parameters of pilocarpine in children.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Glaucoma |
|---|
|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
In children, the tear duct should be occluded with a finger for 1 minute to reduce systemic absorption.
Primary Congenital Glaucoma: Cases of paradoxical increases in IOP have been reported in children. Be aware of that when controlling intraocular pressure (IOP).
[SmPC]
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Carbonic anhydrase inhibitors | ||
|---|---|---|
| S01EC01 | ||
| S01EC03 | ||
| Beta blocking agents | ||
|---|---|---|
| S01ED01 | ||
| Prostaglandin analogues | ||
|---|---|---|
| S01EE03 | ||
| S01EE01 | ||
| S01EE04 | ||
| Other antiglaucoma preparations | ||
|---|---|---|
| S01EX | ||
| OTHER ANTIGLAUCOMA PREPARATIONS | ||
|---|---|---|
| S01EX | ||
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References
- Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2008
- Teva Nederland BV, SmPC Pilocarpine 2% (RVG 57399) 26-09-2016, www.geneesmiddeleninformatiebank.nl
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Changes
Changes
