Travoprost

Generic name
Travoprost
Brand name
ATC Code
S01EE04

Travoprost

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

The general trend shows that plasma exposure to the free acid of travoprost after local administration of travoprost is extremely low in all age groups that were evaluated.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Glaucoma
  • Ocular
    • 0 years up to 18 years
      • In the affected eye: 1 drop(s)/dose Once daily in the evening.
      • Only a few studies have been carried out into the use of travoprost in children

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Ocular hyperaemia, eyelash growth, eyelid erythema, keratitis, increased tear production and photophobia

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

ANTIGLAUCOMA PREPARATIONS AND MIOTICS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Parasympathomimetics
S01EB01
Carbonic anhydrase inhibitors
S01EC01
S01EC03
Beta blocking agents
S01ED01
Prostaglandin analogues
S01EE03
S01EE01
Other antiglaucoma preparations
S01EX
OTHER ANTIGLAUCOMA PREPARATIONS
S01EX

References

  1. SPC Travatan (Alcon Laboratories) 27/11/2006, EU/1/01/199/001-002 (02-03-2015)
  2. Yanovitch TL, et al, Travoprost in children: adverse effects and intraocular pressure response, J AAPOS, 2009, Feb;13(1), 91-3

Changes

Therapeutic Drug Monitoring


Overdose