- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Hypertensive crisis |
|---|
|
| Acute hypertension |
|---|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Consult a nephrologist: experience in children is very limited. Be aware of the possibility of reflex tachycardia.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Dihydropyridine derivatives | ||
|---|---|---|
| C08CA01 | ||
| C08CA05 | ||
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References
- Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
- Heijden, van der AJ et al, Werkboek Kindernefrologie, VU Uitgeverij, 2002, 1e druk
- Lurbe E, et al, Management of high blood pressure in children and adolescents: recommendations of the European Society of Hypertension, J Hypertens, 2009, Sep;27(9), 1719-42
- Mastropietro CW et al., Nicardipine for Hypertension Following Aortic Coarctectomy or Superior Cavopulmonary Anastomosis, World J Pediatr Congenit Heart Surg., 2016, Jan;7(1), 32-5
- Liviskie CJ, et al., Nicardipine for the treatment of neonatal hypertension during extracorpeal membrane oxygenation, Pediatr Cardiol, 2019, 40, 1041-5
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Changes
Changes
