- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
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Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
T½ intravasal: 4-5 hours. Note: the intravasal half-life is not the same as the biological half-life (relationship between duration of the effect and time). After 3 hours, the volume-increasing effect has decreased by 50%.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Plasma replacement |
|---|
|
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
Overfilling, hypersensitivity reactions (urticaria, anaphylaxis, fever), haemodilution (extension of the bleeding time at high concentrations) and renal function disorders (at high concentrations).
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Be aware of the potential for overfilling: pulmonary oedema and congestive heart failure.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Blood substitutes and plasma protein fractions | ||
|---|---|---|
| B05AA01 | ||
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Reference
- Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
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Changes
Changes
