- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Urinary incontinence, overactive bladder syndrome, neurogenic bladder |
|---|
|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Children can be often more sensitive to parasympatholytic drugs; accurate regulation of the dosage is therefore required.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Acidifiers | ||
|---|---|---|
| G04BA01 | ||
| Drugs for urinary frequency and incontinence | ||
|---|---|---|
| G04BD04 | ||
| G04BD06 | ||
| G04BD08 | ||
| G04BD07 | ||
| G04BD09 | ||
| Drugs used in erectile dysfunction | ||
|---|---|---|
| G04BE03 | ||
| G04BE08 | ||
| Other urologicals | ||
|---|---|---|
| G04BX16 | ||
| OTHER UROLOGICALS | ||
|---|---|---|
| G04BX16 | ||
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References
- Verpoorten C, et al, The neurogenic bladder: medical treatment. , Pediatr Nephrol. , 2008, May;23(5), 717-25
- Aslan AR, et al, Conservative management in neurogenic bladder dysfunction., Curr Opin Urol., 2002, Nov;12(6), 473-7
- Buyse G, et al, Intravesical oxybutynin for neurogenic bladder dysfunction: less systemic side effects due to reduced first pass metabolism, J Urol, 1998, Sep;160(3 Pt 1), 892-6
- Ferrara P, et al, Side-effects of oral or intravesical oxybutynin chloride in children with spina bifida, BJU Int, 2001, May;87(7), 674-8
- Guerra LA, et al, Intravesical oxybutynin for children with poorly compliant neurogenic bladder: a systematic review, J Urol, 2008, Sep;180(3), 1091-7
- Haferkamp A, et al, Dosage escalation of intravesical oxybutynin in the treatment of neurogenic bladder patients, Spinal Cord, 2000, Apr;38(4), 250-4
- Kaplinsky R, et al, Expanded followup of intravesical oxybutynin chloride use in children with neurogenic bladder, J Urol, 1996, Aug;156(2 Pt 2), 753-6
- Lazarus J., Intravesical oxybutynin in the pediatric neurogenic bladder, Nat Rev Urol, 2009, Dec;6(12), 671-4
- Lose G, et al, Intravesical oxybutynin for treating incontinence resulting from an overactive detrusor, BJU Int, 2001, Jun;87(9), 767-73
- Verpoorten C, et al, The neurogenic bladder: medical treatment., Pediatr Nephrol., 2008, May;23(5), 717-25
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Changes
Changes
