- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Available formulations
No information is present at this moment.
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Dosages
| West’s syndrome |
|---|
|
| Insomnia |
|---|
|
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
Psychiatric and paradoxical reactions can occur in children in particular, with restlessness, agitation, aggression, delusions, fits of anger, nightmares, hallucinations, inappropriate behaviour and changes in the mental condition. Rare: in infants and young children: bronchial hypersecretion leading to aspiration/lung inflammation
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Use with caution in infants and young children. Monitor for signs of hypersalivation and increased bronchial secretions. Caution is also advised in the case of pre-existing conditions such as dysphagia, gastroesophageal reflux and aspiration tendencies.
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
| Barbiturates, plain | ||
|---|---|---|
| N05CA01 | ||
| Aldehydes and derivatives | ||
|---|---|---|
| N05CC01 | ||
| Benzodiazepine derivatives | ||
|---|---|---|
| N05CD08 | ||
| N05CD07 | ||
| Other hypnotics and sedatives | ||
|---|---|---|
| N05CM18 | ||
| N05CM21 | ||
| Melatonin receptor agonists | ||
|---|---|---|
| N05CH01 | ||
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
References
- Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
- Kamps WA et al, Werkboek ondersteundende behandeling kinderoncologie, VU Uitgeverij, 2005
- Ratiopharm Nederland BV, SPC Nitrazepam (RVG 52656), www.cbg-meb.nl, Geraadpleegd 29 oktober 2010, http://db.cbg-meb.nl/IB-teksten/h52656.pdf
- Accord Healthcare B.V., SmPC Nitrazepam (RVG 08687) 1-02-2019 , www.geneesmiddeleninformatiebank.nl
- Actavis Group PTC ehf, SmPC Apodorm (MT 0000-05989) 17-11-2020, www.legemiddelsok.no
- Accord Healthcare B.V., SmPC Nitrazepam (RVG 08687) 1-02-2019, www.geneesmiddeleninformatiebank.nl
A second drug has not been selected yet.
Press ‘drugs’ followed with and select second drug from list to add the second drug to the comparison.
Changes
Changes
