- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
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Available formulations
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Dosages
| Productive coughing |
|---|
|
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications in children
Children under 2 years.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
The liquid formulations can contain alcohol; caution is needed when using them in young children because of the possibility of alcohol intoxication. Allowance should be made in everyday activities for dizziness occurring.
Using bromhexine as a mucolytic is not recommended in children aged under 2 because paradoxical reactions can occur (“filling up”). Mucolytics can obstruct the respiratory tract of children aged under 2 years as a result of the physiological characteristics of the respiratory tract in this age group. The ability to
cough up slime may be limited.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Expectorants | ||
|---|---|---|
| R05CA | ||
| Mucolytics | ||
|---|---|---|
| R05CB | ||
| R05CB01 | ||
| R05CB06 | ||
| R05CB13 | ||
| R05CB16 | ||
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References
- Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
- Boehringer Ingelheim BV, SPC Bisolvon (RVG 20431, 06053), www.cbg-meb.nl, Geraadpleegd 14 november 2012, http://db.cbg-meb.nl/IB-teksten/h06053.pdf
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Changes
Changes
