- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
The absorption on an empty stomach is minimal.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Enterobiasis |
|---|
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| Ascariasis, trichuriasis, toxocariasis and hookworm infections |
|---|
|
| Taenia Solium infection |
|---|
|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
Very rare: in infants: fever, convulsions and erythema multiforme.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
There is little experience of use in children younger than 2 years.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Benzimidazole derivatives | ||
|---|---|---|
| P02CA03 | ||
| Tetrahydropyrimidine derivatives | ||
|---|---|---|
| P02CC01 | ||
| Imidazothiazole derivatives | ||
|---|---|---|
| P02CE01 | ||
| Avermectines | ||
|---|---|---|
| P02CF01 | ||
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References
- Hartwig NC, et al, Vademecum pediatrische antimicrobiele therapie, 2005
- Johnson&Johnson Consumer BV, SPC Vermox (RVG 06513) 08-02-2016, www.cbg-meb.nl
- Mediq Farma BV, SmPC Mebendazol (RVG 111026) 10-10-2017, www.geneesmiddeleninformatiebank.nl
- KNMP, Zelfzorgstandaard Wormen, https://www.thuisarts.nl/wormen, 2017, augustus
- TEVA, SmPC Mebendazol (RVG 108851) 17-12-2018, www.geneesmiddeleninformatiebank.nl
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Changes
Changes
