Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Cinnarizine

Generic name
Cinnarizine
Brand name
ATC Code
N07CA02

Pharmacokinetics in children

No information

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

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Available formulations

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Dosages

Travel sickness
  • Oral
    • 5 years up to 12 years
      • 12.5 mg/dose take 0.5-2 hours before travelling; repeat every 6-8 hours during the journey if necessary.
    • 12 years up to 18 years
      • 25 mg/dose take 0.5-2 hours before travelling; repeat every 6-8 hours during the journey if necessary.

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Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications in children

Gebruik bij prematuren en neonaten.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

(young) children are extra sensitive to cinnarizine, particularly due to it penetrating into the central nervous system.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. TEVA, SPC Cinnarizine 25 mg (RVG 55114) 09-01-2017, www.geneesmiddeleninformatiebank.nl, h

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Changes

Changes