Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Natriumpicosulfaat

Generic name
Natriumpicosulfaat
Brand name
ATC Code
A06AB08

Pharmacokinetics in children

Sodiumpicosulfate is  locally active in the colon and are not absorbed in detectable amounts.

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

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Dosages

Constipation
  • Oral
    • ≥ 4 years
      [2] [3]
      • 2.5 - 5 mg/day in 1 dose Take in the evening..
        • If the effect is insufficient, the dosage can be increased on a trial basis, dosage average 1 mg per 5 kg body weight, max 10 mg/day
        • In functional constipation and impaction: in combination with macrogol for 3 days.
        • Do not use for longer than 2 weeks. Effect diminishes with daily use, therefore preferably use intermittently.
    • 4 years up to 10 years
      • 2.5 - 5 mg/day in 1 dose Take in the evening..
        • If the effect is insufficient, the dosage can be increased on a trial basis, dosage average 1 mg per 5 kg body weight, max 10 mg/day
        • In functional constipation and impaction: in combination with macrogol for 3 days.
        • Do not use for longer than 2 weeks. Effect diminishes with daily use, therefore preferably use intermittently.
    • 10 years up to 18 years
      • 5 - 10 mg/day in 1 dose Take in the evening..
        • In functional constipation and impaction: in combination with macrogol for 3 days.
        • Do not use for longer than 2 weeks. Effect diminishes with daily use, therefore preferably use intermittently.

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Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

In children, apply only on the advice of a physician. In children < 4 years of age, sodium picosulfate is less effective, as in these children the intestinal microflora is not yet sufficiently developed.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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References

  1. M. Groeneweg- kinder MDL arts,, Expert opinie , Correspondentie 08-07-2018
  2. Sanofi, SmPC Laxoberal 7,5mg/ml Tropfen zum Einnehmen_Laxoberal 5mg Tabletten (6926.00.01_6926.00.00), 07/2017
  3. Sanofi, SmPC Laxoberal 2,5mg Weichkapseln (6926.00.04), 03/2007
  4. Opella Healthcare Austria GmbH, SmPC Guttalax 7,5 mg/ml Tropfen (17160), 12/2024

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Changes

Changes