- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
Taking into account the difference in body weight, the pharmacokinetics of ziprasidone in paediatric patients aged 10 to 17 years were comparable to those in adult patients.
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Bipolar disorder |
|---|
|
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Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
In children with bipolar disorder (10 to 17 years): very common (≥ 10%): sedation, drowsiness, headache, fatigue, nausea, and dizziness
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Ziprasidone is associated with a dose-related prolongation of the QT interval. Do not exceed the maximum dose.
An unequal distribution of the daily dose with morning doses 20 mg or 40 mg lower than evening doses can be considered.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Phenothiazines with aliphatic side-chain | ||
|---|---|---|
| N05AA02 | ||
| Butyrophenone derivatives | ||
|---|---|---|
| N05AD01 | ||
| N05AD05 | ||
| Indole derivatives | ||
|---|---|---|
| N05AE05 | ||
| Diphenylbutylpiperidine derivatives | ||
|---|---|---|
| N05AG02 | ||
| Diazepines, oxazepines, thiazepines and oxepines | ||
|---|---|---|
| N05AH02 | ||
| N05AH03 | ||
| N05AH04 | ||
| Lithium | ||
|---|---|---|
| N05AN01 | ||
| Other antipsychotics | ||
|---|---|---|
| N05AX12 | ||
| N05AX13 | ||
| N05AX08 | ||
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References
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Changes
Changes
