Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pyrantel

Generic name
Pyrantel
Brand name
ATC Code
P02CC01

Pharmacokinetics in children

Pyrantel is only absorbed from the gastrointestinal tract to a small extent [SmPC Helmex].

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dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

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Available formulations

No information is present at this moment.

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Dosages

Infections with gastrointestinal parasites (Enterobius vermicularis/Oxyuren (pinworm), Ancylostoma duodenale (hookworm))
  • Oral
    • 6 months up to 18 years
      [1] [2]
      • 10 mg/kg/dose, once only. Max: 1 g/dose.
      • Oxyuren: repeat therapy after 2 – 4 weeks
        Other infections:  if necessary repeat therapy after max. 6 months

Infections with Necator americanus (American hookworm)
  • Oral
    • 6 months up to 18 years
      [2]
      • 10 mg/kg/day in 1 dose. Max: 1 g/dose. for 3 days..
      • Alternative: 20 mg/kg/dose, max. 1 g/dose for 2 days

         If necessary repeat therapy after max. 6 months

Infections with Ascaris lumbricoides (roundworm)
  • Oral
    • 6 months up to 18 years
      [1] [2]
      • 5 mg/kg/dose, once only. Max: 1 g/dose.
      • If necessary repeat therapy after max. 6 months

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Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

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Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

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Benzimidazole derivatives
P02CA03
P02CA01
Imidazothiazole derivatives
P02CE01
Avermectines
P02CF01

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References

  1. InfectoPharm, SmPC Helmex® 250 mg Kautabletten (6120655.00.00), 05/2020
  2. InfectoPharm, SmPC Helmex® 250 mg/5 ml Suspension zum Einnehmen (7289.00.00), 05/2020

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Changes

Changes