- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No data available
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dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
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Available formulations
No information is present at this moment.
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Dosages
| Pyridoxine-dependent epilepsy |
|---|
|
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Renal impaiment in children > 3 months
No information available on dose adjustment in renal impairment.
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The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
Apnea, prolonged cerbral depression after initial dose.
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The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions in children
Resuscitation and intensive care facilities should be available when pyridoxalphosphate is used intravenously due to the risk of apnea and cerebral depression.
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Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
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| Other plain vitamin preparations | ||
|---|---|---|
| A11HA05 | ||
| A11HA01 | ||
| A11HA02 | ||
| A11HA04 | ||
| A11HA03 | ||
| A11HA08 | ||
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References
- Blau, Hoffmann, Leonard and Clarke, Physicians guide to the treatment and follow-up of metabolic diseases,, Springer, 2006
- Baxter P., Pyridoxine or pyridoxal phosphate for intractable seizures?, Arch Dis Child, 2005, May;90(5), 441-2
- Wang HS et al, Pyridoxal phosphate is better than pyridoxine for controlling idiopathic intractable epilepsy, Arch Dis Child., 2005, May;90(5), 512-5
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Changes
Changes
