L-citrulline

Generic name
L-citrulline
Brand name
ATC Code
V06DD

L-citrulline

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Urea cycle defects, ornithine transcarbamoylase (OTC) deficiency, carbamoyl phosphate synthetase (CPS) deficiency
  • Oral
    • 0 years up to 18 years
      • 100 - 150 mg/kg/day in 3 - 4 doses.
      • Dose depending on plasma glutamine concentration.

        Treatment by or after consultations with a paediatric specialist (metabolic disorders) who has experience using L-citrulline for this indication.

         

    • 0 years up to 18 years
      [2]
      • 100 - 150 mg/kg/day in 3 - 4 doses.
      • Dose depending on plasma glutamine concentration.

        Treatment by or after consultations with a paediatric specialist (metabolic disorders) who has experience using L-citrulline for this indication.

         

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

GENERAL NUTRIENTS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

OTHER NUTRIENTS
V06DD

References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. Blau, Hoffmann, Leonard and Clarke, Physicians guide to the treatment and follow-up of metabolic diseases., Springer, 2006

Changes

Therapeutic Drug Monitoring


Overdose