Pharmacokinetics in children
No information on use in children.
dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
Available formulations
No information is present at this moment.
Dosages
| Prevention of endometrial hyperplasia in oestrogen treatment for puberty induction or growth inhibition |
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Renal impaiment in children > 3 months
Caution is needed in acute kidney impairment, as medroxyprogesterone may cause moderate fluid retention.
The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects
No information is present at this moment.
The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
PROGESTAGENEN
This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.
| Estren derivatives |
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G03DC03
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G03DC02
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References
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Noordam C et al,, Werkboek Kinderendocrinologie, digitale publicatie op www.nvk.nl (alleen leden), 2010
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NKFK Workinggroup Acute Kidney Impairment, Extrapolation of KNMP risk analysis "Impaired renal function" for adults to children, 20 Dec 2021
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Pozo J., Ascertainment and treatment of delayed puberty., Horm Res, 2003, 60 Suppl 3:, 35-48
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Normann EK., Height reduction in 539 tall girls treated with three different dosages of ethinyloestradiol., Arch Dis Child., 1991, 66(11), 1275-8
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Grüters A., Effect of different oestrogen doses on final height reduction in girls with constitutional tall stature., Eur J Pediatr., 1989, 149(1), 11-3
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Drop SL, Sex steroid treatment of constitutionally tall stature, Endocr Rev., 1998, 19(5), 540-58
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Matthews D., Hormone supplementation for pubertal induction in girls., Arch Dis Child, 2017, 102(10), 975-80
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de Waal WJ., [Hormonal therapy of constitutionally tall children], Ned Tijdschr Geneeskd, 1998, 142(13), 693-7
Therapeutic Drug Monitoring
Overdose