Formoterol

Generic name
Formoterol
Brand name
ATC Code
R03AC13
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Formoterol

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Maintenance treatment for asthma
  • Inhalation
    • 6 years up to 18 years
      • (Formoterolfumaratemonohydrate) 12 - 24 microg./day in 1 - 2 doses. Max: 48 microg./day.

      • Up to 24 mcg twice daily in severe asthma.
        Formoterol should always be prescribed in combination with an inhalation corticosteroid


        FORMULATIONS
        4-7 yrs: dosing aerosol + holding chamber with a mouthpiece.
        ≥ 7 yrs: dosing aerosol. Option: Dry powder inhaler (Diskus).
Acute asthma attack
  • Inhalation
    • 1 month up to 18 years
      • (Formoterolfumaratemonohydrate) 12 microg./dose, as required, max. 4 times daily.

      • NOTE: This is a temporary dosing recommendation to provide an alternative to salbutamol deficiency. There limited data on the use in children under 6 years of age.

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

Central nervous system stimulation effects, expressed as overstimulation and hyperactivity, have been reported sporadically after inhalation of β2-sympathomimetics. These effects have primarily been seen in children younger than 12

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Before prescribing formoterol, a bronchodilatory response should be confirmed by making an FEV1 measurement before and after beta-2 mimetics. An alternative to the lung function measurements in children aged less than 6 years is a good response to a LABA or SABA that has been administered. There is insufficient data known about the use of formoterol in children aged under 6 years.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

ADRENERGICS, INHALANTS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Alpha- and beta-adrenoreceptor agonists
R03AA01
Selective beta-2-adrenoreceptor agonists
R03AC02
R03AC12
R03AC03
Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
R03AK08
R03AK11
R03AK10
R03AK07
R03AK06
Adrenergics in combination with anticholinergics incl. triple combinations with corticosteroids
R03AL01
R03AL02

References

  1. AstraZeneca BV, SmPC Oxis (RVG 21026) 12-03-2024, www.geneesmiddeleninformatiebank.nl
  2. NVK, Richtlijn Astma bij Kinderen, 2013

Changes

Therapeutic Drug Monitoring


Overdose