Corifollitropine alfa

Generic name
Corifollitropine alfa
Brand name
ATC Code
G03GA09
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Corifollitropine alfa

Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information is present at this moment.

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Hypogonadotropic hypogonadism, induction of puberty
  • Subcutaneous
    • ≥ 14 years and ≥ 60 kg
      • 150 microg./dose once every 2 weeks.

      • After 12 weeks: Combine administration of corifollitropin alfa with hCG 
        Only on prescription from pediatric endocrinologist

    • ≥ 14 years and < 60 kg
      • 100 microg./dose once every 2 weeks.

      • After 12 weeks: Combine administration of corifollitropin alfa with hCG 
        Only on prescription from pediatric endocrinologist

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects in children

In male adolescents:
Common (1-10%): vomiting. Hot flashes. Pain at the injection site.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Use is not recommended in adolescents who have been treated with GnRH, gonadotropins or testosterone in the past.

An increased concentration of endogenous FSH indicates primary testicular failure; in that case, treatment with corifollitropin α and hCG is of no use.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

GONADOTROFINEN EN ANDERE OVULATIESTIMULERENDE MIDDELEN

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Gonadotropins
G03GA01

Reference

  1. N.V. Organon, SmPC Elonva (EU/1/09/609/001) Rev 23, 05-04-2023, www.ema.europa.eu

Changes

Therapeutic Drug Monitoring


Overdose