Selenium

Generic name
Selenium
Brand name
ATC Code
A12CE02
Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

The absorption is approximately 45-95%

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Selenium deficiency
  • Oral
    • 1 month up to 1 year
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose
    • 1 year up to 4 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 60 microg./day.
    • 4 years up to 7 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 90 microg./day.
    • 7 years up to 11 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 130 microg./day.
    • 11 years up to 15 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 200 microg./day.
    • 15 years up to 18 years
      • Initial dose: (Selenium) 2 microg./kg/day in 1 dose
      • Maintenance dose: 1 microg./kg/day in 1 dose. Max: 250 microg./day.
Maintenance requirement for selenium in TPN
  • Intravenous
    • 1 month up to 18 years
      • 1 - 2 microg./kg/day, continuous infusion. Max: 30 microg./day.

Renal impaiment in children > 3 months

GFR ≥10 ml/min/1.73m2: Dose adjustment not required.

GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions

No information available on specific warnings and precautions in children.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

OTHER MINERAL SUPPLEMENTS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Sodium
A12CA01
Zinc
A12CB01
Magnesium
A12CC05
A12CC01
A12CC04
A12CC03
A12CC02
Other mineral products
A12CX
MAGNESIUM
A12CC05
A12CC01
A12CC04
A12CC03
A12CC02
OTHER MINERAL PRODUCTS
A12CX

References

  1. Rademaker C.M.A. et al, Geneesmiddelen-Formularium voor Kinderen, 2007
  2. Biosyn Arzneimittel GmbH, SmPC Selenase (RVG 22907) 17-12-2014, www.geneesmiddeleninformatiebank.nl

Changes

Therapeutic Drug Monitoring


Overdose