Docusate sodium (either combined with sorbitol or not)
Generic name
Docusate sodium (either combined with sorbitol or not)
Brand name
ATC Code
A06AG10
- Dosages
- Side effects in children
- Warnings & precautions in children
- Contra-indications in children
-
Interactions - PK
- Renal impairment
- References
Pharmacokinetics in children
No information
dose recommendation of formulary compared to licensed use (on-label versus off-label)
No information is present at this moment.
Available formulations
No information is present at this moment.
Dosages
| Constipation |
|---|
|
Renal impaiment in children > 3 months
GFR ≥10 ml/min/1.73m2: Dose adjustment not required.
GFR <10 ml/min/1.73m2: A general recommendation on dose adjustment cannot be provided.
The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here
Side effects in children
Abdominal pain can occur after administration. It usually resolves after 30 minutes
The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here
Contra-indications
No information available on specific contra indications in children.
The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here
Warnings & precautions
No information available on specific warnings and precautions in children.
Interactions
The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here
DRUGS FOR CONSTIPATION
This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.
| Softeners, emollients | ||
|---|---|---|
| A06AA01 | ||
| Contact laxatives | ||
|---|---|---|
| A06AB02 | ||
| A06AB08 | ||
| A06AB06 | ||
| A06AB06 | ||
| A06AB58 | ||
| Bulk-forming laxatives | ||
|---|---|---|
| A06AC01 | ||
| Osmotically acting laxatives | ||
|---|---|---|
| A06AD12 | ||
| A06AD11 | ||
| A06AD65 | ||
| A06AD65 | ||
| A06AD15 | ||
| A06AD65 | ||
| Enemas | ||
|---|---|---|
| A06AG | ||
| A06AG10 | ||
| A06AG04 | ||
| A06AG11 | ||
| A06AG01 | ||
| Other drugs for constipation | ||
|---|---|---|
| A06AX01 | ||
| A06AX02 | ||
References
- Essential Pharma (M) Limited, SPC Norgalax (RVG 14141) 10-01-2019, www.geneesmiddeleninformatiebank.nl
- Rademaker C.M.A. et al. ., Geneesmiddelen-Formularium voor Kinderen, 2008
- Bekkali NL et al, Rectal fecal impaction treatment in childhood constipation: enemas versus high doses oral PEG, Pediatrics, 2009, Dec;124(6), e1108-15
- Tabbers et al, Dutch Paediatric Association guideline " Obstipation in children 0-18 years", www.nvk.nl, 2015
Changes
Therapeutic Drug Monitoring
Overdose
