Biotin

Generic name
Biotin
Brand name
ATC Code
A11HA05
Dosages
Side effects in children
Warnings & precautions in children
Contra-indications in children

Interactions
PK
Renal impairment
References

Pharmacokinetics in children

No information

dose recommendation of formulary compared to licensed use (on-label versus off-label)

No information is present at this moment.

Available formulations

No information is present at this moment.

Dosages

Holocarboxylase deficiency
  • Intravenous
    • 0 years up to 18 years
      [1]
      • 10 - 40 mg/day in 3 doses.

      • Treatment by or after consultations with a paediatric specialist (metabolic disorders) who has experience with using biotin for this indication.

    • 0 years up to 18 years
      • 10 - 40 mg/day in 3 doses.

      • Treatment by or after consultations with a paediatric specialist (metabolic disorders) who has experience with using biotin for this indication.

    • 0 years up to 18 years
      • 10 - 40 mg/day in 3 doses.

      • Treatment by or after consultations with a paediatric specialist (metabolic disorders) who has experience with using biotin for this indication.

Renal impaiment in children > 3 months

No information available on dose adjustment in renal impairment.

The complete list of all undesirable drug reactions can be found in the national Summary of Product Characteristics (SmPC) – click here

Side effects

No information is present at this moment.

The complete list of all contra-indications can be found in the national Summary of Product Characteristics (SmPC) – click here

Contra-indications

No information available on specific contra indications in children.

The complete list of all warnings and precautions can be found in the national Summary of Product Characteristics (SmPC) – click here

Warnings & precautions in children

Sodium benzoate for tackling secondary hyperammonaemia is contraindicated in organic acid disorders. Patients with organic acid disorders have a tendency to develop hypokalaemia. Potassium levels must only be corrected if there is diuresis.

Interactions

The complete list of all interactions can be found in the national Summary of Product Characteristics (SmPC) – click here

OTHER PLAIN VITAMIN PREPARATIONS

This pages provides a list of drugs from the same ATC class for comparison. This does not necessarily mean that these drugs are interchangeable.

Other plain vitamin preparations
A11HA01
A11HA06
A11HA02
A11HA04
A11HA03
A11HA08

Reference

  1. Blau, Hoffmann, Leonard and Clarke, Physicians guide to the treatment and follow-up of metabolic diseases., Springer, 2006

Changes

Therapeutic Drug Monitoring


Overdose